RBFOX2 and dilated cardiomyopathy: RNA-binding Protein Fox-1 Homolog 2 (RBFOX2) is a splicing regulator implicated in differentiation of myofibroblasts to skeletal muscle, and diminished expression previously associated with pressure-overload-mediated progression of dilated cardiomyopathy/heart failure; [34] potential impact on airway smooth muscle has not been described.