One possible explanation for the relationship between acute liver injury andnon-hepatotropic parasite infections might be an interaction between CYP2E1 and IL-6.CYP2E1 is a member of the cytochrome C superfamily, and it has prominent roles inmetabolising a wide variety of substances like acetaminophen (Kessova & Cederbaum 2003). Here, CYCS is linked to parasitic infectious disease.