The C-reactive protein-to-albumin (CRP/ALB) ratio has been reported to be a more accurate prognostic value in patients with various malignancies than the modified Glasgow prognostic score (mGPS) (Kinoshita et al. 2015; Xu et al. 2015), which is also calculated from the serum CRP and ALB concentration, and we previously reported on the prognostic significance of the CRP/ALB ratio in patients with CRC who underwent curative surgery (Shibutani et al. 2016). This evidence concerns the gene ALB and colorectal carcinoma.