It has been shown that a single nucleotide polymorphism (SNP) of IL28B gene (IL-28B rs12979860 C/T) predicts hepatitis C treatment induced viral clearance (Ge et al., 2009; Halfon et al., 2011; Lin et al., 2011; Lindh et al., 2011; Luo et al., 2013) and is associated with spontaneous resolution of hepatitis C infection (Duggal et al., 2013; Kurbanov et al., 2011; Shi et al., 2012; Thomas et al., 2009; Tillmann et al., 2010). The gene discussed is IFNL3; the disease is hepatitis C virus infection.