Potentially interesting targets in this context are the endogenous opioid and the central oxytocin system, since both systems are known to functionally interact with the eCB system (Cota et al., 2006; Russo et al., 2012), take part in the regulation of social behavior (Insel and Fernald, 2004; MacDonald and Leary, 2005) and have also been implicated in BPD (Stanley and Siever, 2010; Roepke et al., 2012). Here, OXT is linked to Borderline personality disorder.