Similarly, the pooled HR for non-Asian subgroup for OS was 2.61(95%CI 1.51–4.52, P = 0.001), which was significantly higher than 1.85(95%CI 0.96–3.55, P = 0.064) for Asian subgroup, suggesting that high VEGF-C expression might be more closely associated with poor survival for BC patients in non-Asian countries. The gene discussed is VEGFC; the disease is breast cancer.