ADIPOQ and obesity due to melanocortin 4 receptor deficiency: More specifically, dysregulation of adipokines has been demonstrated to be associated with obesity, type 2 diabetes, and hypertension [62] These all are in keeping with our findings where significant or marked positive correlations were found between the serum HDL or adiponectin levels or both of these parameters with the relative abundances of Bacteroides, Prevotella, Akkermansia, Lactobacillus, Roseburia, and Ruminococcus.