However, we found that the IL-10 rs1800871 C/T genotype was associated with increased OS in low-grade glioma cases (3-year survival rate = 13.1%, median survival = 12 months, Log-rank p = 0.019, HR=0.745, 95% CI=0.573–0.969, p = 0.028), but not high-grade cases. This evidence concerns the gene IL10 and central nervous system cancer.