Our results are consistent with other investigations that showed T. spiralis excretory-secretory antigen-stimulated dendritic cells alleviated experimental autoimmune encephalomyelitis or DSS-induced colitis through inducing Treg that increased the secretion of IL-4, IL-10 and TGF-β [4, 41, 42]. The gene discussed is TGFB1; the disease is colitis.