Indeed, the repertoire of proteins reported to be nitrated in AD has expanded to include many critical mediators of essential cellular functions, such as aldolases A and C, peroxiredoxin 2, neuropolypeptide H3, glutamate dehydrogenase, phosphoglycerate mutase1, TPI, and H+-transporting ATPase [114, 136, 137]. The gene discussed is TPI1; the disease is Alzheimer disease.