POMC and epilepsy: According to the TSC management recommendations published in 2012 [8], treatment options for TSC-associated epilepsy in children and adolescents include various antiepileptic drugs (AEDs), with Vigabatrin being the drug of first choice, Adrenocorticotropic hormone (ACTH), epilepsy surgery, the ketogenic diet (KD) and vagus nerve stimulation (VNS) [9].