However, a single lncRNA can regulate multiple target genes, and a powerful inflammation-related lncRNA might also target multiple inflammation genes, for example, H19 targets TGFβ1 in prostate cancer cells [55]; TGFβ1 is a key regulator in CCA inflammation [1], suggesting the pivotal role of inflammation regulation by H19. This evidence concerns the gene TGFB1 and cholangiocarcinoma.