ALB and tuberculosis: However, results related to 25(OH)D have to be interpreted carefully, as 25(OH)D mainly reflects protein-bound vitamin D and may not represent the level of free active form of vitamin D. During inflammation, similarly to levels of several other blood acute-phase proteins, the concentration of albumin decreases and might modify 25(OH)D result [27], while one study showed no change in blood VDBP during the first 8 weeks of TB treatment [28].