BAG5 and cancer: Saos2-R175H, Saos2-R248W, Saos2-R273H, Saos2-con cells and HCT116p53R248W/−, HCT116p53−/− cells with or without BAG5 knockdown by siRNA were treated with 5-FU, one of the most commonly used chemotherapeutic agent for human cancer.