LAMA2 and neoplasm: Interestingly, structural proteins, such as KERA and LAMA2, were up-regulated in the muscle of both Folfiri-treated animals and tumor-bearing mice (Figures 3B,C; Table S4), unlike other proteins, such as MYOZ2, overexpressed in the muscle of C26 hosts and, conversely, down-regulated in the muscle of chemotherapy-treated animals (Table S4).