CRP and substance abuse: Two trials were also excluded because they were conducted on school children (Sibinga et al., 2013; Schonert-Reichl et al., 2015); along with a further two systematic reviews taking into account MBIs with adolescents (Zoogman et al., 2015; Felver et al., 2016), and another two trials which were performed with substance abusers (Marcus et al., 2003) and with a C-reactive protein (CRP) level >3 mg/ml (Malarkey et al., 2013).