However, Drosophila dystroglycanopathy models, including null alleles of dystroglycan, do not have defects in myoblast migration and myofiber formation (Nakamura et al, 2010), indicating that the muscle phenotypes observed in rumi flies are not caused by alterations in dystroglycan. This evidence concerns the gene DAG1 and neuromuscular disease caused by qualitative or quantitative defects of alpha-dystroglycan.