In the present study, we found that the relative mRNA levels of most of amino acid transporter EAAT1, PAT1, PAT2 and ASCT2 in the COS group were increased or presented uptrend compared with that in the control group, which was consistent with previous report that mTOR increased total amino acid transporter gene expression with enhanced surface expression in mouse lymphoma cells, and the great expression of amino acid transporter increased the mTOR activity [40]. The gene discussed is SLC38A7; the disease is lymphoma.