Moreover, LYVE-1 gene expression followed a similar pattern (Supplementary Figure S3B), and mouse VEGF-C and VEGF-D mRNAs were induced by NCoR depletion (Supplementary Figure S3C), suggesting again that the absence of this corepressor induces changes in the tumor cells that affect the tumor microenvironment. The gene discussed is NCOR1; the disease is neoplasm.