As shown in Figure 5A, in parallel with the changes in VEGF-C and VEGF-D expression, the presence of tumor DNA in the sentinel node was decreased in animals inoculated with TR ®-expressing cells, while NCoR depletion resulted in a significant increase in the amount of tumor DNA reaching the node and in a partial reversion of the inhibitory effect of TR ®. The gene discussed is VEGFD; the disease is neoplasm.