Moreover, compared with xenografts tumor tissues injected with con-siRNA, the 14-3-3ζ-siRNA-injection decreased the formation of intratumoral capillary tubes (as determined by the CD31 positive microvessels, Figure 2B), attenuated the ability of proliferation (as determined by the Ki-67 staining, Figure 2C), and enhanced the apoptosis (as determined by TUNEL staining, Figure 2D). This evidence concerns the gene MKI67 and neoplasm.