In comparison to normal controls, the GAC transcript was significantly overexpressed in AML with complex cytogenetics (p=0.0007) and moderately higher in AML with FLT3-ITD/NPM1 gene mutations (p=0.0077); it was significantly lower in AML with trisomy 8 (p=0.001; Figure 1D). Here, NPM1 is linked to acute myeloid leukemia.