GBP1 and infection: Our analysis of macrophages lacking the GBPs on chromosome 3, including GBP1,2,3,5, and 7 [98], suggests that these GBPs are not required for cytosolic lysis and subsequent inflammasome activation following infection with either wild type L. monocytogenes or mutants with increased bacteriolysis in the cytosol, including ΔyvcK and ΔprkA mutants.