Taken together, our results indicated that alternatively activated MΦ (IL-10 treatment) show an iron-release phenotype and stimulate tumor cell survival and proliferation, whereas classically activated MΦ (LPS/IFNγ) induce an iron-sequestration phenotype with functional consequences on inhibition of tumor cell proliferation, which is in line with previous reports [6, 32]. Here, IL10 is linked to neoplasm.