To investigate the in vivo relevance of the PPP1R11/TLR2 pathway, we assayed white blood cell (WBC) pellets for PPP1R11 and TLR2 expression in control and S. aureus-infected patients from our Acute Lung Injury Registry and Biospecimen Repository (Coon et al., 2015). The gene discussed is PPP1R11; the disease is acute lung injury.