ADM and pheochromocytoma: Adrenomedullin, a 52-amino acid peptide with structural homology to calcitonin gene-related peptide, was initially isolated from human phaeochromocytoma.11 Adrenomedullin is synthesised by many mammalian tissues, including the adrenal medulla, endothelial and vascular smooth muscle cells, myocardium and central nervous system.12