In the family-based association analyses carried out by Serajee et al. (2006), the most significant results were the apparent association of autism, in a broad diagnosis of the disease, with rs736707 in intron 59 and rs362691 in exon 22 of the RELN. Li et al. (2008) also showed a significant genetic association between rs736707 in intron 59 and ASD in a Han Chinese population. Here, RELN is linked to autism.