Approximately half of the cancers that developed in both genotypes of mice were sarcoma [10 of 23 (43.5%) for Mtbp+/+ and 15 of 34 (44.1%) for Mtbp+/−; Figure 2C], occurring at a mean age of 806 days for Mtbp+/+ and 743 days for Mtbp+/− mice (p = 0.1547, Supplemental Figure S1). This evidence concerns the gene MTBP and cancer.