Although, twice the proportion of Mtbp wild-type control mice were cancer free at time of death (7 of 23, 30.4%) compared to Mtbp heterozygous mice (5 of 34, 14.7%; Figure 2D), the Mtbp+/− mice lived an average of 836.4 days compared to 640.3 days for wild-type controls (Supplemental Figure S1). Here, MTBP is linked to cancer.