TNFSF13B and neuromyelitis optica: Of particular note, rituximab was followed by severe clinical and radiologic deterioration with myelitis and active (yet asymptomatic) lesions in the pons and medulla oblongata within a few weeks after infusion in patient 1, which is reminiscent of the possibly BAFF-mediated deterioration reported in some NMO patients after commencement of rituximab [64].