Serum MMP-2 levels could be associated to ascending aortic aneurysms in a previous study [24] and we found, that serum MMP-2 levels for patients with ascending aortic aneurysms significantly lower than serum levels in healthy controls (190.3 +/- 48.3 ng/ml vs 240.3 +/- 46.4 ng/ml). The gene discussed is MMP2; the disease is Ascending tubular aorta aneurysm.