Promotes invasion and inhibits apoptosis by inhibiting PTEN in LSCC [28]; promotes cell growth, migration and invasion in NPC by inducing VEGF-A and HSP70 expression [23, 32]; promotes proliferation, migration and invasion, and inhibits apoptosis by recruiting EZH2 to silence E-cadherin in OSCC [29, 30, 31]. Here, PTEN is linked to nasopharyngeal carcinoma.