BDNF and Anxiety: longum NCC3001 enhanced hippocampal brain-derived neurotrophic factor messenger RNA and reduced anxiety-like behavior in mice infected with the non-invasive parasite T Muris50 and B. breve 6330 increased brain-derived neurotrophic factor total variants in healthy rats.51 It is thus of interest whether brain-derived neurotrophic factor levels and neurogenesis are heightened in humans following psychobiotic ingestion, thus having a key role in the impact of psychobiotic consumption upon the central nervous system.