Recent studies reported germline mutations in the Phd1 and Phd2 genes in association with systemic hypertension and pheochromocytoma, paraganglioma–polycythemia syndrome.36 The possibility of defects in Phd genes in the aforementioned pediatric lung disorders has not yet been explored. Here, EGLN1 is linked to hereditary pheochromocytoma-paraganglioma.