Treatment options include panretinal or focal laser photocoagulation, photodynamic therapy, intravitreal or periocular triamcinolone injection, oral pentoxifylline, hyperbaric oxygen, intravitreal anti-vascular endothelial growth factor (anti-VEGF) and intravitreal silicone application prior to brachytherapy.133,134,135 Missotten et al.136 showed that VEGF-A levels are higher in the aqueous humour of both treated and untreated uveal melanoma patients. Here, VEGFA is linked to uveal melanoma.