VEGFA and polyp: However, in the randomized controlled study EVEREST, no difference was found between PDT and combined PDT and anti-VEGF therapy in terms of VA improvement or polyp regression (71.4% and 77.8%, respectively), and the rate of polyp regression with anti-VEGF therapy alone was low (28.6%).13 Similarly, when we compared the results from our patients treated with PDT or combined PDT and IVB injection during the mean 24 months of follow-up, we found post-treatment anatomic and functional recovery in both groups, and no statistically significant difference emerged in the results.