Interestingly, it has been suggested to use PPARs as target for cancer treatment, and several PPAR agonists, in particular acting on PPAR-γ, represent promising therapeutic tools as antitumoral agents [75]; PPAR-γ agonists were reported to inhibit cell growth and to induce apoptosis in several cancer cell lines in vitro and in vivo [76–86], including NB cells [87, 88]. This evidence concerns the gene PPARA and neuroblastoma.