HNPP is due to PMP22 haploinsufficiency (Adlkofer et al, 1995, 1997) and is modeled by the Pmp22+/− mouse, whose nerves are characterized by tomacula (Adlkofer et al, 1995, 1997; Bai et al, 2010). This evidence concerns the gene PMP22 and hereditary neuropathy with liability to pressure palsies.