We provide evidence that an intergenic enhancer region on 6q23, associated with numerous autoimmune diseases and nominally assigned to TNFAIP3 although over 200 kb from the nearest gene, makes allele-specific, regulatory contact with IL20RA, the target of an existing drug and located 680 kb away from the associated region. The gene discussed is TNFAIP3; the disease is autoimmune disease.