Additional somatic mutations in cancer-associated genes included missense mutations in TP53 (c.743G > A, p.R248Q), MAX (c.179G > A, p.R60Q), BRAF (c.1447A > G, p.K483E), and RPTOR (c.2252C > T, p.A751V), and a nonsense mutation in ROS1 (c.1176 T > A, p.C392*). The gene discussed is TP53; the disease is cancer.