PPARGC1A and hepatocellular carcinoma: To assess whether NT‐PGC‐1α activates transcription of endogenous gluconeogenic genes, we transduced HepG2 hepatoma cells with recombinant adenovirus carrying the cDNA encoding mouse NT‐PGC‐1α (Ad‐NT‐PGC‐1α) or control adenovirus expressing GFP (Ad‐GFP).