A number of animal studies have shown that excessive intrauterine androgen exposure results in many problems in offspring, such as excessive weight gain, visceral and subcutaneous fat accumulation, increased fat cell volume, impaired glucose tolerance, decreased insulin sensitivity and lipid metabolism disorders (Demissie et al. 2008, Roland et al. 2010, Yan et al. 2013). This evidence concerns the gene INS and Impaired glucose tolerance.