In the NeuroX data, 1.3% (89/6,647) of PD samples had established PD-causing mutations (defining Known Mutation-PD cases), comprising single mutations in autosomal dominant genes (78 LRRK2, 1 VPS35) and biallelic mutations in autosomal recessive genes (10 PARK2). This evidence concerns the gene VPS35 and Parkinson disease.