Multivariable analyses revealed age (OR 1.04, 95% CI 1.02–1.06), male gender (OR 2.26, 95% CI 1.17–4.36), and the number of catheters and drainages before diagnosis of BSI (OR for every additional catheter = 1.14, 95% CI 1.04–1.25) as independent predictors for delirium (adjusted for SAPS [simplified acute physiology score] II, Riker Sedation-Agitation Scale [SAS], Sequential Organ Failure Assessment [SOFA] score, dementia and/or leukoencephalopathy, and albumin levels). The gene discussed is ALB; the disease is dementia.