Another correlated variant (r2 >0.7) on chromosome 1 was also genotyped, namely rs1767429 (p = 9 × 10−3), which was also located within ALPL. The strongest evidence of association with ovarian cancer risk in BRCA2 mutation carriers was observed for rs2233025 (p = 5 × 10−3), located at 1p32.22 within the MAD2L2 gene. Here, ALPL is linked to ovarian cancer.