For examples, the overexpression of RPSA may be positively correlated with the angiogenesis of lung cancer49, 50, the overexpression of RPL19 promotes malignant proliferation of lung cancer cells51, and the underexpression of RPS3, a critical regulator of DNA repair and apoptosis52, might accelerate the development of lung cancer. The gene discussed is RPS3; the disease is lung carcinoma.