As it is known, IL-4 is associated with proliferation and differentiation of activated B cells, IgE switching, induction of eosinophil transmigration across endothelium, regulation of Th2 responses in allergic diseases, and effects on the synthesis of chemokines such as CCL11, CCL24, CCL26, and CCL13 [62–64]. This evidence concerns the gene CCL11 and allergic disease.