Fifteen virulence factors were found, such as aggregation substance (agg), collagen adhesin (ace), hyaluronidase (hylA and hylB), endocarditis- and biofilm-associated pili (ebpA, ebpB, and ebpC), and E. faecalis endocarditis antigen A (efaAfs) (2). Here, ACE is linked to endocarditis.