TP53 and cancer: Based on these results and those of others in cancer cells showing the protective effect of autophagy activation from CDDP or 5‐FU toxicity (Harhaji‐Trajkovic et al, 2009; Guo et al, 2014), we suggest that the suppression of autophagy through reversible p53 inhibition in these TP53‐mutant tumors may account in part for their sensitization to CDDP.