Future studies on the efficacy of AZA and oral steroids as well as on that of oral steroids as stand-alone therapy in MOG autoimmunity should take into account that a recent retrospective analysis suggested a better response rate to high-dose azathioprine (2.5-3 mg/kg) than to standard treatment (1-1.5 mg/kg) in AQP4-IgG-positive NMOSD [58]. The gene discussed is MOG; the disease is Autoimmunity.