In addition, bioinformatics assessment of microarray profiles obtained from dissociated fresh primary tumors (GSE39396), which had been fluorescence activated cell sorting (FACS) selected into specific endothelial, epithelial, leukocyte and fibroblast populations, confirmed that MET gene expression is significantly higher in tumor epithelial cells when compared to endothelial cells or leukocyte or fibroblast cells within the TME (p < 0.0001) (Supplementary Figure S5). Here, MET is linked to neoplasm.