Here, we found Twist1 could decrease the levels of Bax/Bcl-2 in CNE2 cells after exposure to 6Gy radiation over 72 hours (Figure 4D-4F), indicated that Twist1 induced radioresistance in large part due to restraining NPC cells apoptosis by altering Bax/Bcl-2. Here, BAX is linked to nasopharyngeal carcinoma.